mini-scantm radiotlc linear scanner lablogic systems (LabLogic Systems Ltd)
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![(a, b) Recovery: percentage of [ 89 Zr]Zr-oxine remaining in solution over time when formulated in HEPES buffer only and in presence of 5% EtOHorvarying concentrations of polysorbate 80. Mean ± SDof n = 3 separate experiments. (c) Yield of [ 89 Zr]Zr-oxine over time in HEPES buffers (pH 7.9) containing NaOH ( n = 5) or NaHCO 3 ( n = 4), measured by <t>radioTLC.</t> (d) Stability: [ 89 Zr]Zr-oxine as percentage oftotal 89 Zr activity in solution over 7 days, measured by radioTLC (n = 3), in original 100 pLformulation or after 10-fold dilution with H 2 O. (e) Formation rate and radiochemical yield of [ 89 Zr]Zr-oxine as a function of oxalate content and 89 Zr decay. [ 89 Zr]Zr-oxalate in 1 M oxalic acid (1.1-1.5 MBq/μL on day 0, approximately 4-5 days after production in the cyclotron) was added to 20 μL aliquots of kit formulation on day of reception (day 0) and 4 subsequent days. To keep total 89 Zr activity constant, increasing volumes of [ 89 Zr]Zr-oxalate solution were added on each day, resulting in increasing concentrations of oxalate ions in the final product. Mean ± SD of n = 3 separate experiments.](https://pub-med-central-images-cdn.bioz.com/pub_med_central_ids_ending_with_6765/pmc07116765/pmc07116765__EMS115486-f002.jpg)
Mini Scantm Radiotlc Linear Scanner Lablogic Systems, supplied by LabLogic Systems Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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1) Product Images from "A kit formulation for the preparation of [ 89 Zr]Zr(oxinate) 4 for PET cell tracking: White blood cell labelling and comparison with [ 111 In]In(oxinate) 3"
Article Title: A kit formulation for the preparation of [ 89 Zr]Zr(oxinate) 4 for PET cell tracking: White blood cell labelling and comparison with [ 111 In]In(oxinate) 3
Journal: Nuclear medicine and biology
doi: 10.1016/j.nucmedbio.2020.09.002
Figure Legend Snippet: (a, b) Recovery: percentage of [ 89 Zr]Zr-oxine remaining in solution over time when formulated in HEPES buffer only and in presence of 5% EtOHorvarying concentrations of polysorbate 80. Mean ± SDof n = 3 separate experiments. (c) Yield of [ 89 Zr]Zr-oxine over time in HEPES buffers (pH 7.9) containing NaOH ( n = 5) or NaHCO 3 ( n = 4), measured by radioTLC. (d) Stability: [ 89 Zr]Zr-oxine as percentage oftotal 89 Zr activity in solution over 7 days, measured by radioTLC (n = 3), in original 100 pLformulation or after 10-fold dilution with H 2 O. (e) Formation rate and radiochemical yield of [ 89 Zr]Zr-oxine as a function of oxalate content and 89 Zr decay. [ 89 Zr]Zr-oxalate in 1 M oxalic acid (1.1-1.5 MBq/μL on day 0, approximately 4-5 days after production in the cyclotron) was added to 20 μL aliquots of kit formulation on day of reception (day 0) and 4 subsequent days. To keep total 89 Zr activity constant, increasing volumes of [ 89 Zr]Zr-oxalate solution were added on each day, resulting in increasing concentrations of oxalate ions in the final product. Mean ± SD of n = 3 separate experiments.
Techniques Used: Activity Assay, Formulation
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